Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503752 | 0.81 | HTR2C (0.50) | ALDH1A1KDM4ERXFP1KMT2AMEN1 | |
| SCHEMBL7980169 | 0.81 | PTGDR2 (0.58) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL6602729 | 0.81 | L3MBTL1 (0.74) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2CDC7 | |
| SCHEMBL6503373 | 0.77 | L3MBTL1 (0.57) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL16399964 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1L3MBTL1KMT2A | |
| SCHEMBL7593177 | 0.75 | L3MBTL1 (0.46) | ALDH1A1KDM4ERXFP1L3MBTL1KMT2A | |
| SCHEMBL6427866 | 0.75 | KDM4E (0.57) | ALDH1A1KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL6502591 | 0.74 | L3MBTL1 (0.47) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL8408123 | 0.74 | L3MBTL1 (0.47) | L3MBTL1PTGDR2 | |
| SCHEMBL6505829 | 0.73 | KDM4E (0.56) | ALDH1A1KDM4ERXFP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |