Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003208 | 0.87 | L3MBTL1 (0.62) | L3MBTL1TP53MAPTABL1PTGDR2 | |
| SCHEMBL6503373 | 0.84 | L3MBTL1 (0.57) | L3MBTL1MAPTPTGDR2KDM4EALDH1A1 | |
| SCHEMBL6495754 | 0.83 | MDM2 (0.47) | MDM2KMOTP53MAPTRPA1 | |
| SCHEMBL18003210 | 0.79 | TP53 (0.37) | KMOTP53MAPTABL1PTGDR2 | |
| SCHEMBL6502484 | 0.77 | L3MBTL1 (0.58) | L3MBTL1TP53MAPTPTGDR2KDM4E | |
| SCHEMBL6602729 | 0.77 | L3MBTL1 (0.74) | L3MBTL1PTGDR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12875848 | 0.75 | L3MBTL1 (0.56) | L3MBTL1KMOMAPTPTGDR2KDM4E | |
| SCHEMBL18003704 | 0.75 | L3MBTL1 (0.67) | L3MBTL1MAPTABL1PTGDR2KDM4E | |
| SCHEMBL27500333 | 0.75 | L3MBTL1 (0.56) | L3MBTL1MAPTCOPS5PTGDR2KDM4E | |
| SCHEMBL5238288 | 0.74 | L3MBTL1 (0.58) | L3MBTL1PTGDR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |