Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503419 | 0.92 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1NPSR1GAAPPARG | |
| SCHEMBL6495930 | 0.76 | MEN1 (0.46) | ALDH1A1L3MBTL1GAAKMT2AMEN1 | |
| SCHEMBL6503416 | 0.68 | POLB (0.46) | ALDH1A1NPSR1GAAKMT2AMEN1 | |
| SCHEMBL12682640 | 0.64 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1NPSR1GAAKMT2A | |
| SCHEMBL18119752 | 0.62 | KMT2A (0.56) | ALDH1A1NPSR1GAAKMT2AMEN1 | |
| SCHEMBL19987418 | 0.62 | ALDH1A1 (0.56) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL28570980 | 0.61 | KMT2A (0.55) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL28570981 | 0.61 | KMT2A (0.55) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL21695366 | 0.61 | KMT2A (0.58) | ALDH1A1L3MBTL1NPSR1KMT2AMEN1 | |
| SCHEMBL19232114 | 0.61 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |