Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495933 | 0.92 | ALDH1A1 (0.43) | ALDH1A1NPSR1L3MBTL1FFAR1PPARG | |
| SCHEMBL6503416 | 0.75 | POLB (0.46) | ALDH1A1NPSR1MAPTKMT2AGAA | |
| SCHEMBL6495930 | 0.68 | MEN1 (0.46) | ALDH1A1L3MBTL1MAPTKMT2AGAA | |
| SCHEMBL3914469 | 0.62 | MAPT (0.55) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL14254797 | 0.60 | ALDH1A1 (0.55) | ALDH1A1TAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL6236094 | 0.60 | MEN1 (0.55) | ALDH1A1NPSR1L3MBTL1PPARGNPC1 | |
| SCHEMBL1247602 | 0.60 | PPARG (0.66) | ALDH1A1NPSR1FFAR1PPARGMAPT | |
| SCHEMBL2095754 | 0.59 | MAPT (0.59) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6930080 | 0.59 | PPARG (0.76) | FFAR1PPARG | |
| SCHEMBL6929446 | 0.59 | PPARG (0.76) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |