Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.44 |
| ▸ | PPARD | Q03181 | 16/20 | 0.44 |
| ▸ | PPARG | P37231 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495709 | 0.85 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL6504014 | 0.83 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL6496923 | 0.80 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL6495941 | 0.79 | ALDH1A1 (0.33) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL6502319 | 0.79 | PPARD (0.69) | PPARAPPARDPPARG | |
| SCHEMBL6506184 | 0.79 | ALOX15 (0.46) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL4329462 | 0.79 | ALOX15 (0.44) | PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL4334796 | 0.79 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL6503847 | 0.78 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL4329833 | 0.78 | ALOX15 (0.46) | PPARAPPARDPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |