Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IARS1 | P41252 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495704 | 0.86 | LMNA (0.33) | ALDH1A1LDHAIARS1ALOX15MAPT | |
| SCHEMBL6495800 | 0.83 | LDHA (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL6495944 | 0.79 | PPARA (0.44) | ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL4329066 | 0.77 | GAA (0.47) | ALDH1A1LDHAL3MBTL1ALOX15PKM | |
| SCHEMBL4333218 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL6506184 | 0.76 | ALOX15 (0.46) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL4333251 | 0.76 | ALOX15 (0.57) | LDHAIARS1ALOX15LMNAALOX12 | |
| SCHEMBL4329833 | 0.75 | ALOX15 (0.46) | ALDH1A1LDHAALOX15PKMPPARG | |
| SCHEMBL4329462 | 0.74 | ALOX15 (0.44) | ALDH1A1LDHAALOX15PKMPPARG | |
| SCHEMBL6498892 | 0.74 | PPARA (0.44) | LDHAALOX15PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |