Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.54 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501450 | 0.87 | GABRA1 (0.46) | GABRA1GABRB2CA12CA1CA2 | |
| SCHEMBL11750664 | 0.82 | GABRA1 (0.56) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL423306 | 0.80 | GABRA1 (0.54) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL16414537 | 0.80 | GABRA1 (0.54) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL9712914 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL9712566 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL580709 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2CLCN2CA12CA1 | |
| SCHEMBL18378584 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2CLCN2CA12CA1 | |
| Nitrogen SCHEMBL10979876 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2CLCN2CA12CA1 | |
| Hydrochloric Acid SCHEMBL5013100 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2CLCN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252862-B2 | Silane coupling agents for filled rubbers | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2190912-B1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-20100261826-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-10-14 | — | — | US | disclosed |
| EP-2190912-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-06-02 | — | — | EP | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| EP-1727858-B1 | COUPLING AGENTS BETWEEN FILLER AND ELASTOMER | BASF SE (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009034016-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (CH) | 2009-03-19 | — | — | WO | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
| EP-1928888-A1 | FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY | Ciba Holding Inc. (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007039416-A1 | FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |
| EP-1727858-A1 | COUPLING AGENTS BETWEEN FILLER AND ELASTOMER | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005059022-A1 | COUPLING AGENTS BETWEEN FILLER AND ELASTOMER | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-06-30 | — | — | WO | disclosed |
| US-6521681-B1 | Phenol-free stabilization of polyolefin fibres | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | GABRA1 3665/4885GABRB2 4440/4885CLCN2 4510/4885 |
| US-20100261826-A1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | RER1, REV1, RIOX2 | GABRA1 3569/4885GABRB2 4469/4885CLCN2 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.