Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649683 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2NLRP3ALDH1A1TDP1 | |
| SCHEMBL13105884 | 0.83 | GABRA1 (0.46) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 | |
| SCHEMBL424866 | 0.83 | L3MBTL1 (0.50) | GABRA1GABRB2PTGS2ALDH1A1TDP1 | |
| SCHEMBL502187 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1HSD17B10CA1CA2 | |
| SCHEMBL6241927 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 | |
| SCHEMBL8093727 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 | |
| SCHEMBL2857937 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 | |
| SCHEMBL10299397 | 0.79 | CA12 (0.52) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 | |
| SCHEMBL9881695 | 0.79 | CA12 (0.61) | NLRP3ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL19443663 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2PTGS2NLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906279-B2 | Manufacturing method of polarizing plate protective film, polarizing plate protective film, polarizing plate, and liquid crystal display device | KONICA MINOLTA OPTO, INC. (JP) | 2014-12-09 | — | — | US | disclosed |
| US-8569405-B2 | Additive mixtures for styrenic polymers | BASF SE (DE) | 2013-10-29 | — | — | US | disclosed |
| US-8518302-B2 | Stabilization of organic materials | BASF SE (DE) | 2013-08-27 | — | — | US | disclosed |
| US-8252862-B2 | Silane coupling agents for filled rubbers | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-20120088869-A1 | STABILIZATION OF ORGANIC MATERIALS | GERSTER MICHELE (CH) | 2012-04-12 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8105504-B2 | Stabilization of organic materials | BASF SE (DE) | 2012-01-31 | — | — | US | disclosed |
| EP-2190912-B1 | SILANE COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| EP-2238199-B1 | ADDITIVE MIXTURES FOR STYRENIC POLYMERS | BASF SE (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-1786859-B1 | STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-5428177-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0648765-A1 | Process for the production of 3-arylbenzofuranones | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0644190-A1 | Benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1995-03-22 | — | — | EP | disclosed |
| US-5369159-A | Heat, oxidation and radiation resistance for polymers | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| US-5367008-A | 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers | CIBA-GEIGY CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0608198-A1 | Cyclic diphenylacetonenitriles as stabilisers | CIBA-GEIGY AG (CH) | 1994-07-27 | — | — | EP | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| EP-0589839-A1 | 3-(Dihydrobenzofuran-5-yl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088869-A1 | STABILIZATION OF ORGANIC MATERIALS | LPO, AOX1, SOD1 | GABRA1 3552/4885GABRB2 4501/4885PTGS2 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.