SCHEMBL6497293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6500809	0.90	NPC1 (0.43)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6500583	0.89	NPC1 (0.42)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6489260	0.89	ALDH1A1 (0.49)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6501627	0.89	MMP13 (0.43)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6488167	0.88	S1PR4 (0.43)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6487729	0.87	ALDH1A1 (0.57)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6500577	0.87	MAPKAPK2 (0.45)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6496009	0.85	MEN1 (0.49)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6498810	0.83	CHRNB2 (0.46)	NPC1RAB9AL3MBTL1ALDH1A1HPGD
	SCHEMBL6490768	0.82	MAPKAPK2 (0.41)	NPC1RAB9AL3MBTL1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.