Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6103445 | 0.89 | DHODH (0.42) | DHODHCTSKBCAT2BCAT1TRPV4 | |
| SCHEMBL6495847 | 0.79 | AR (0.44) | DHODHCTSKTRPV4L3MBTL1 | |
| SCHEMBL7970802 | 0.78 | DHODH (0.42) | DHODHCTSKL3MBTL1 | |
| SCHEMBL5420508 | 0.77 | CTSK (0.47) | CTSK | |
| SCHEMBL8829582 | 0.76 | DHODH (0.42) | DHODHCTSKL3MBTL1 | |
| SCHEMBL6504729 | 0.76 | DHODH (0.45) | DHODHBCAT2BCAT1 | |
| SCHEMBL6506687 | 0.76 | CTSK (0.44) | DHODHCTSK | |
| SCHEMBL10417411 | 0.76 | DHODH (0.38) | DHODHGAAATML3MBTL1 | |
| SCHEMBL6496551 | 0.75 | TRPV4 (0.36) | DHODHBCAT2BCAT1TRPV4 | |
| SCHEMBL6495187 | 0.75 | L3MBTL1 (0.43) | DHODHCTSKATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7076578-A | — | — | None | — | — | JP | disclosed |
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| EP-0597360-B1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| JP-H0776578-A | SUBSTITUTED TRIAZOLINONES | BAYER AG | 1995-03-20 | — | — | JP | disclosed |
| EP-0597360-A1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |