Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 9/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498287 | 1.00 | MC4R (0.38) | MC4RDPP4DPP7TAAR1FFAR1 | |
| SCHEMBL14944889 | 0.80 | DPP4 (0.43) | MC4RDPP4 | |
| SCHEMBL20397729 | 0.79 | HTR2A (0.43) | DPP4P2RX7 | |
| SCHEMBL5696571 | 0.79 | TAAR1 (0.48) | TAAR1 | |
| Hydrochloric Acid SCHEMBL31497138 | 0.78 | ALOX15 (0.36) | MC4R | |
| SCHEMBL14640299 | 0.77 | USP2 (0.51) | MC4R | |
| SCHEMBL17483509 | 0.77 | MC4R (0.41) | MC4RDPP4DPP7FFAR1FFAR4 | |
| SCHEMBL30543993 | 0.77 | USP2 (0.51) | MC4R | |
| SCHEMBL17208960 | 0.76 | MC4R (0.36) | MC4RDPP4TAAR1FFAR1FFAR4 | |
| SCHEMBL5927564 | 0.76 | GABRA1 (0.38) | MC4RDPP4TAAR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124652-A1 | Guanidino compounds | BOYCE RUSTUM (US) | 2005-06-09 | — | — | US | disclosed |
| US-20030195187-A1 | Guanidino compounds | CHIRON CORPORATION | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195187-A1 | Guanidino compounds | MC4R, MC2R, GPR4 | MC4R 1/4885DPP4 659/4885DPP7 2214/4885 |
| US-20050124652-A1 | Guanidino compounds | MC4R, MC2R, GPR4 | MC4R 1/4885DPP4 659/4885DPP7 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.