Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 7/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509473 | 0.87 | KDM4E (0.65) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6497435 | 0.86 | HRH3 (0.61) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5064660 | 0.84 | ACHE (0.77) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6507060 | 0.84 | MEN1 (0.70) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6506556 | 0.84 | ALDH1A1 (0.70) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5059245 | 0.83 | ALDH1A1 (0.76) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6497411 | 0.83 | MEN1 (0.63) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6499049 | 0.83 | KDM4E (0.60) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6496798 | 0.82 | KDM4E (0.59) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL3644401 | 0.82 | KDM4E (0.79) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | ALDH1A1 1071/4885GAA 2177/4885LMNA 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.