Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503743 | 0.71 | — | — | |
| SCHEMBL6244342 | 0.68 | — | — | |
| SCHEMBL6496406 | 0.64 | — | — | |
| SCHEMBL6497751 | 0.64 | — | — | |
| SCHEMBL6498524 | 0.61 | CA2 (0.33) | MAPTKMT2A | |
| SCHEMBL6496797 | 0.61 | THRB (0.33) | KMT2A | |
| SCHEMBL6499187 | 0.60 | THRB (0.38) | MAPTKMT2A | |
| SCHEMBL18527595 | 0.59 | — | — | |
| SCHEMBL16925206 | 0.58 | SIRT1 (0.41) | MAPTKMT2A | |
| SCHEMBL1969487 | 0.58 | ALDH1A1 (0.42) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |