Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1649376 | 0.87 | POLB (0.66) | POLBHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL6499867 | 0.83 | PDE5A (0.50) | POLBHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL1647455 | 0.83 | GLA (0.64) | POLBHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL1647843 | 0.81 | KDM4E (0.62) | POLBHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL20782410 | 0.77 | GPBAR1 (0.68) | POLBHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL6639187 | 0.75 | KMT2A (0.54) | POLBALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL394951 | 0.74 | L3MBTL1 (0.64) | POLBHPGDALDH1A1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL6199458 | 0.74 | KMT2A (0.53) | POLBALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL17363910 | 0.74 | HSD17B10 (0.62) | HPGDALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL6644972 | 0.73 | S1PR3 (0.53) | POLBHSD17B10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130983-A1 | Pyrrolopyrimidinone derivatives, process for preparation thereof, and method of using and composition comprising them | IN2GEN CO., LTD. (KR) | 2005-06-16 | — | — | US | disclosed |
| EP-1362858-A1 | Pyrrolopyrimidinone derivates, process of preparation and use | SK Chemicals Co., Ltd. (KR) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130983-A1 | Pyrrolopyrimidinone derivatives, process for preparation thereof, and method of using and composition comprising them | DHPS, SDHA, FDPS | POLB 319/4885HPGD 173/4885ALDH1A1 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.