Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.46 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503892 | 0.87 | OPRM1 (0.73) | OPRM1OPRD1OPRK1KMT2ASLC22A1 | |
| SCHEMBL6496131 | 0.86 | OPRM1 (0.56) | OPRM1OPRD1OPRK1CYP2C19KMT2A | |
| SCHEMBL12121940 | 0.86 | KMT2A (0.58) | OPRM1OPRD1OPRK1KMT2AMEN1 | |
| SCHEMBL6498839 | 0.86 | HSD11B1 (0.63) | OPRM1OPRD1OPRK1CYP2C19KMT2A | |
| SCHEMBL17888245 | 0.82 | OPRM1 (0.64) | OPRM1OPRD1OPRK1CYP2C19KMT2A | |
| SCHEMBL351393 | 0.81 | AKR1C1 (0.55) | OPRM1CYP2C19KMT2AMEN1LMNA | |
| SCHEMBL6504241 | 0.78 | OPRM1 (0.65) | OPRM1OPRD1OPRK1KMT2ASLC22A1 | |
| SCHEMBL3485961 | 0.78 | AKR1C1 (0.62) | OPRM1CYP2C19KMT2AMEN1LMNA | |
| SCHEMBL1048151 | 0.78 | AKR1C1 (0.68) | OPRM1CYP2C19KMT2AMEN1CYP1A2 | |
| SCHEMBL7063427 | 0.78 | OPRM1 (0.50) | OPRM1OPRD1OPRK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | OPRM1 494/4885OPRD1 565/4885OPRK1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.