Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447441 | 0.83 | LMNA (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL6074384 | 0.83 | ADRB3 (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL6075074 | 0.83 | LMNA (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL7243938 | 0.83 | ADRB3 (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL9445125 | 0.83 | ADRB3 (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL6074523 | 0.83 | LMNA (0.65) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL7106207 | 0.82 | PNMT (0.48) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL7452691 | 0.82 | LMNA (0.64) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL9688351 | 0.81 | ADRB2 (0.72) | LMNAADRB3KDM4EADRB2ADRB1 | |
| SCHEMBL7244119 | 0.80 | ADRB3 (0.61) | LMNAADRB3KDM4EADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6888012-B2 | Reducing an alpha -haloketone compound by asymmetric hydrogen transfer in presence of a group 9 transition metal compound having a substituted or unsubstituted cyclopentadienyl group and an optically active diamine compound | AJINOMOTO CO., INC. (JP) | 2005-05-03 | — | — | US | disclosed |
| EP-1346972-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOHYDRIN COMPOUND | Ajinomoto Co., Inc. (JP) | 2003-09-24 | — | — | EP | disclosed |