Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.40 |
| ▸ | CHRNG | P07510 | 2/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRND | Q07001 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3888929 | 0.99 | PARP1 (0.42) | PARP1SLC6A2SLC6A3SMN1; SMN2CHRNA1 | |
| SCHEMBL6505974 | 0.85 | PARP1 (0.44) | PARP1SLC6A2SLC6A3SMN1; SMN2CHRNA1 | |
| SCHEMBL6499506 | 0.85 | GABRP (0.41) | SMN1; SMN2NPC1PKMRAB9AKCNH2 | |
| SCHEMBL6505647 | 0.84 | PARP1 (0.43) | PARP1SLC6A2SLC6A3CHRNA1CHRNG | |
| Bromide SCHEMBL3892578 | 0.84 | PARP1 (0.43) | PARP1SLC6A2SLC6A3SMN1; SMN2CHRNA1 | |
| Bromide SCHEMBL3890064 | 0.84 | GABRP (0.41) | SMN1; SMN2NPC1PKMRAB9AKCNH2 | |
| Bromide SCHEMBL3891895 | 0.83 | GABRP (0.46) | CYP2C19TDP1ALDH1A1GABRPGABRD | |
| Bromide SCHEMBL3889498 | 0.83 | PARP1 (0.42) | PARP1SLC6A2SLC6A3CHRNA1CHRNG | |
| Bromide SCHEMBL3894827 | 0.83 | SLC6A2 (0.39) | PARP1SLC6A2SLC6A3SMN1; SMN2CHRNA1 | |
| Bromide SCHEMBL3886815 | 0.83 | CES2 (0.46) | PARP1SLC6A2SLC6A3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1364949-A1 | JNK INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | PARP1 3236/4885SLC6A2 4327/4885SLC6A3 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.