Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417375 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL9779465 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL8917488 | 0.80 | KMT2A (0.67) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL321369 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL7385779 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL501352 | 0.74 | ALDH1A1 (0.82) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL13118343 | 0.73 | LMNA (1.00) | ALDH1A1MAPTKMT2ALMNACYP2C19 | |
| SCHEMBL6979432 | 0.73 | L3MBTL1 (0.51) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL6100704 | 0.73 | L3MBTL1 (0.51) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL21077881 | 0.72 | TSHR (0.71) | ALDH1A1MAPTKMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159470-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159470-A1 | Histone deacetylase inhibitors | HDAC5, HDAC1, HDAC10 | ALDH1A1 4032/4885MAPT 4248/4885KMT2A 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.