Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KMO | O15229 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688379 | 0.84 | ALDH1A1 (0.80) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL6798850 | 0.83 | RAB9A (0.74) | KDM4EALDH1A1GAAKMT2AMAPT | |
| SCHEMBL1517203 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL29717077 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL6498262 | 0.80 | MAPT (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28685766 | 0.80 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL29631156 | 0.80 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL3319386 | 0.80 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL3105857 | 0.79 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL1517128 | 0.79 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | AJITO KEIICHI (JP) | 2005-03-17 | — | — | US | disclosed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | ITGAV, ITGB3, ITGA4 | KDM4E 945/4885ALDH1A1 1967/4885HPGD 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.