Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816064 | 0.82 | GAA (0.51) | ALDH1A1HPGDLMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL6885505 | 0.81 | TSHR (0.58) | ALDH1A1LMNAALOX15HSD17B10TSHR | |
| SCHEMBL5365743 | 0.79 | EPHX1 (0.55) | ALDH1A1HPGDHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1701693 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TSHR | |
| SCHEMBL3062971 | 0.78 | POLB (0.54) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL10814700 | 0.78 | TSHR (0.54) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL3077377 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL11470090 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDALOX15HSD17B10TSHR | |
| SCHEMBL14322322 | 0.76 | TSHR (0.52) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL3077991 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | ALDH1A1 3345/4885HPGD 308/4885LMNA 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.