Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008904 | 0.85 | TSHR (0.52) | TSHRALDH1A1NPC1RAB9APOLB | |
| SCHEMBL76489 | 0.83 | ALDH1A1 (0.67) | TSHRALDH1A1NPC1RAB9APOLB | |
| SCHEMBL14273160 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1NPC1RAB9APOLB | |
| SCHEMBL10814700 | 0.83 | TSHR (0.54) | TSHRALDH1A1NPC1RAB9APOLB | |
| SCHEMBL7672425 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9APOLBHDAC3 | |
| SCHEMBL24747452 | 0.81 | ALDH1A1 (0.60) | TSHRALDH1A1POLBTDP1KMT2A | |
| SCHEMBL6501458 | 0.81 | ALDH1A1 (0.55) | TSHRALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL14322322 | 0.81 | TSHR (0.52) | TSHRALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL7271571 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HSD17B10KMT2AMEN1GAA | |
| SCHEMBL14861320 | 0.81 | LMNA (0.52) | TSHRALDH1A1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103987697-B | Substituted tetrahydroisoquinoline compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2017-04-26 | — | — | CN | claimed |
| EP-0858455-A4 | 4-OXA AND 4-THIA STEROIDS | MERCK & CO INC (US) | 2000-04-12 | — | — | EP | claimed |
| US-5998464-A | 4-Oxa and 4-thia steroids | MERCK & CO., INC. (US) | 1999-12-07 | — | — | US | claimed |
| US-5817802-A | IN IONIZING MEDIUM WITH A TRIALKYLSILANE | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | claimed |
| EP-0858455-A1 | 4-OXA AND 4-THIA STEROIDS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | claimed |
| US-5777134-A | 4-oxa and 4-thia steriods | MERCK & CO., INC. (US) | 1998-07-07 | — | — | US | claimed |
| US-5696266-A | HYDROGENATING DELTA-5-STEROIDAL ENELACTAM DISSOLVED IN SOLVENT IN PRESENCE OF RHODIUM CATALYST | MERCK & CO., INC. (US) | 1997-12-09 | — | — | US | claimed |
| WO-1997015564-A1 | 4-OXA AND 4-THIA STEROIDS | MERCK & CO., INC. (US) | 1997-05-01 | — | — | WO | claimed |
| WO-1996007643-A1 | PROCESS FOR THE STEREOSELECTIVE REDUCTION OF STEROID ENELACTAMS | MERCK & CO., INC. (US) | 1996-03-14 | — | — | WO | claimed |
| EP-0012241-A1 | Use of disazomethine compounds for the dyeing of thermoplastic polyesters in the mass | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-25 | — | — | EP | claimed |
| CN-111196784-B | Aryl uracil compound or agriculturally acceptable salt thereof, preparation method thereof and pesticide composition | 深圳大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-111196784-A | Aryl uracil compound or agriculturally acceptable salt thereof, preparation method thereof and pesticide composition | 深圳大学 | 2020-05-26 | — | — | CN | disclosed |
| US-10556889-B1 | Salvinorin derivatives | Blue Sky Pharmaceuticals, LLC (US) | 2020-02-11 | — | — | US | disclosed |
| CN-105439974-B | A kind of preparation method of lipase inhibitor | 天津药物研究院有限公司 | 2018-01-12 | — | — | CN | disclosed |
| US-20170029395-A1 | SYNTHESIS OF DERIVATIVES OF DICARBAMATES FROM REDUCTION PRODUCTS OF 2-HYDROXYMETHYL-5-FURUFURAL (HMF) | ARCHER DANIELS MIDLAND COMPANY | 2017-02-02 | — | — | US | disclosed |
| US-4891297-A | STORAGE STABILITY, HIGH COLOR DENSITY | FUJI PHOTO FILM CO.,LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0323887-A2 | Heat-sensitive diazo recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |
| US-4835133-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4447515-A | DIACYLAMINE COMPOUND ADDED | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4052371-A | AZO PIGMENT OR DYE HAVING A NAPHTHYL-QUINAZALONE COUPLING COMPONENT | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029395-A1 | SYNTHESIS OF DERIVATIVES OF DICARBAMATES FROM REDUCTION PRODUCTS OF 2-HYDROXYMETHYL-5-FURUFURAL (HMF) | MGMT, TKFC, DMPK | TSHR 3500/4885ALDH1A1 2384/4885NPC1 3817/4885 |
| US-10556889-B1 | Salvinorin derivatives | OPRD1, OPRK1, OPRL1 | TSHR 1164/4885ALDH1A1 866/4885NPC1 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.