Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903975 | 0.89 | CYP11B1 (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6505294 | 0.85 | ALDH1A1 (0.42) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL360712 | 0.81 | CFTR (0.57) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6499767 | 0.80 | CYP3A4 (0.35) | SLC6A2SLC6A4SLC6A3GAASMN1; SMN2 | |
| SCHEMBL6506735 | 0.76 | GAA (0.60) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6501170 | 0.76 | CYP19A1 (0.46) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL1515839 | 0.76 | KCNA5 (0.47) | TDP1GAASMN1; SMN2KCNA5MAPT | |
| SCHEMBL6503338 | 0.75 | CYP19A1 (0.62) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6502611 | 0.75 | POLB (0.51) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6498908 | 0.75 | KMT2A (0.46) | SMN1; SMN2KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | CFTR 3911/4885SLC6A2 4327/4885SLC6A4 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.