Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360712 | 0.86 | CFTR (0.57) | ALDH1A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6501548 | 0.85 | CFTR (0.41) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL3903975 | 0.84 | CYP11B1 (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6502611 | 0.83 | POLB (0.51) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6503338 | 0.83 | CYP19A1 (0.62) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6498870 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6498908 | 0.83 | KMT2A (0.46) | ALDH1A1CYP19A1CYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL8191216 | 0.81 | PTGS2 (0.48) | ALDH1A1CYP3A4L3MBTL1NAMPT | |
| SCHEMBL6504970 | 0.80 | CYP19A1 (0.39) | SLC6A2SLC6A4SLC6A3CYP19A1GAA | |
| SCHEMBL1515700 | 0.80 | LMNA (0.46) | ALDH1A1SLC6A3CYP2A6SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | ALDH1A1 3345/4885CFTR 3911/4885SLC6A2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.