Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501293 | 0.92 | MEN1 (0.32) | MEN1KMT2AUSP2TSHRKDM4E | |
| SCHEMBL6506064 | 0.91 | TSHR (0.41) | MEN1KMT2AUSP2TSHRALDH1A1 | |
| SCHEMBL6504837 | 0.91 | MEN1 (0.32) | MEN1KMT2AUSP2TSHRALDH1A1 | |
| SCHEMBL6427691 | 0.91 | ALDH1A1 (0.33) | MEN1KMT2AUSP2TSHRALDH1A1 | |
| SCHEMBL6501582 | 0.90 | ALDH1A1 (0.35) | KDM4EMAPTALDH1A1LMNAEPHX2 | |
| SCHEMBL6504717 | 0.87 | MMP2 (0.32) | EPHX2 | |
| SCHEMBL6427407 | 0.86 | ALDH1A1 (0.32) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL6501771 | 0.84 | CTPS1 (0.38) | MAPTALDH1A1 | |
| SCHEMBL6426010 | 0.83 | MAPT (0.30) | MAPT | |
| SCHEMBL6427354 | 0.81 | POLQ (0.37) | HTTMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | HTT 3969/4885MEN1 979/4885KMT2A 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.