Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807876 | 0.84 | ABCB1 (0.50) | ABCB1L3MBTL1ALDH1A1GAACA12 | |
| SCHEMBL7531320 | 0.82 | KMT2A (0.43) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL1054893 | 0.81 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1GAAMAPTATM | |
| SCHEMBL2088631 | 0.80 | FFAR4 (0.43) | IDO1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL11324512 | 0.80 | ABCB1 (0.62) | ABCB1L3MBTL1MAPTATMHPGD | |
| SCHEMBL1129749 | 0.79 | PTGS2 (0.46) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8698021 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1MAPTATMHPGD | |
| SCHEMBL2096467 | 0.78 | CA1 (0.41) | IDO1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL7644217 | 0.78 | HRH1 (0.51) | GAA | |
| SCHEMBL5984175 | 0.78 | GABRA1 (0.41) | IDO1L3MBTL1MAPTATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187281-A | Cephalosporin derivative containing guanidyl and preparation method thereof | 广西科技大学 | 2020-05-22 | — | — | CN | claimed |
| EP-2976092-B1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS INC (US) | 2020-04-22 | — | — | EP | claimed |
| EP-3532475-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | Array Biopharma Inc. (US) | 2019-09-04 | — | — | EP | claimed |
| WO-2019005796-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2018081417-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2018-05-03 | — | — | WO | claimed |
| CN-107530259-A | Method using acid amides, acid or ester C glycosides derivatives processing keratin material and the cosmetic composition containing them | 莱雅公司 | 2018-01-02 | — | — | CN | claimed |
| CN-104829632-B | A kind of cephalosporins derivatives of the substituent containing aminodithioformic acid | 中山大学 | 2017-09-29 | — | — | CN | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| EP-3068770-A1 | PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2016-09-21 | — | — | EP | claimed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| US-5393878-A | Pyrimidine nucleosides having cyclopentafuran skeleton | CIBA-GEIGY CORPORATION (US) | 1995-02-28 | — | — | US | claimed |
| WO-1994018329-A2 | SERINE PROTEASE VARIANTS HAVING PEPTIDE LIGASE ACTIVITY | GENENTECH, INC. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5319080-A | Antiviral agents | CIBA-GEIGY CORPORATION (US) | 1994-06-07 | — | — | US | claimed |
| EP-0583338-A1 | METHOD FOR SYNTHESIZING PEPTIDES, NOVEL AMINO ACID DERIVATIVES USED THEREIN, AND METHODS FOR PREPARING SAME. | PROPEPTIDE SA (FR) | 1994-02-23 | — | — | EP | claimed |
| WO-1992019643-A1 | METHOD FOR SYNTHESIZING PEPTIDES, NOVEL AMINO ACID DERIVATIVES USED THEREIN, AND METHODS FOR PREPARING SAME | PROPEPTIDE (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0268963-A1 | Benzazolylthio-carbapenem antibiotics | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0053962-B1 | CEPHALOSPORIN DERIVATIVES AND THEIR PREPARATION | RHONE-POULENC SANTE (FR) | 1985-03-13 | — | — | EP | claimed |
| US-4393228-A | THIOL PROTEASE INHIBITORS, ANTIINFLAMMATORY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | claimed |