Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65021 | 0.82 | IDO1 (0.58) | MAPTL3MBTL1IDO1ALDH1A1HTT | |
| SCHEMBL6549408 | 0.81 | MEN1 (0.43) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL2920835 | 0.80 | ALDH1A1 (0.40) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL164746 | 0.77 | SMN1; SMN2 (0.46) | KMT2AMEN1MAPTL3MBTL1IDO1 | |
| SCHEMBL1405475 | 0.76 | CA1 (0.60) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1405477 | 0.76 | CA1 (0.60) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1807876 | 0.74 | ABCB1 (0.50) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL16287599 | 0.70 | SLC6A3 (0.32) | — | |
| SCHEMBL2096467 | 0.70 | CA1 (0.41) | MAPTIDO1ALDH1A1LMNAMAPK1 | |
| SCHEMBL1054893 | 0.69 | L3MBTL1 (0.56) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198472-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001005816-A1 | AMINE-MODIFIED PSEUDOMYCIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |
| EP-0389437-A1 | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0043247-B1 | PEPTIDES FOR USE IN DETERMINING SERUM THYMIC FACTOR | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-02-01 | — | — | EP | disclosed |
| US-4404133-A | TYROSINE DERIVATIVES, SERUM THYMIC FACTOR ANALOGS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0043247-A1 | Peptides for use in determining serum thymic factor | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-01-06 | — | — | EP | disclosed |