Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 15/20 | 0.36 |
| ▸ | PPARG | P37231 | 13/20 | 0.36 |
| ▸ | PPARD | Q03181 | 10/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506028 | 0.92 | LMNA (0.37) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL6495940 | 0.92 | PPARG (0.38) | PPARAPPARGPPARD | |
| SCHEMBL6504909 | 0.90 | S1PR3 (0.38) | EPHX2PPARAPPARGPPARDITGB1 | |
| SCHEMBL6504440 | 0.85 | EPHX2 (0.36) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6496963 | 0.85 | TP53 (0.39) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6505285 | 0.84 | PPARA (0.43) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6494327 | 0.84 | EPHX2 (0.37) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6502157 | 0.83 | NR1H4 (0.37) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL7685465 | 0.82 | EPHX2 (0.36) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6503712 | 0.82 | PPARA (0.50) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |