Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 11/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505922 | 0.93 | CTSL (0.37) | PPARAPPARGPPARDALDH1A1HPGD | |
| SCHEMBL6498815 | 0.92 | PPARG (0.37) | PPARAPPARGPPARDALDH1A1MAPT | |
| SCHEMBL6503035 | 0.91 | S1PR3 (0.36) | EPHX2PPARAPPARGPPARD | |
| SCHEMBL6494327 | 0.89 | EPHX2 (0.37) | EPHX2NR1H4PPARAPPARGITGB1 | |
| SCHEMBL6502157 | 0.86 | NR1H4 (0.37) | EPHX2NR1H4PPARAPPARGITGB1 | |
| SCHEMBL6504440 | 0.85 | EPHX2 (0.36) | EPHX2NR1H4PPARAPPARGITGB1 | |
| SCHEMBL6496963 | 0.84 | TP53 (0.39) | EPHX2NR1H4PPARAPPARGITGB1 | |
| SCHEMBL6505285 | 0.84 | PPARA (0.43) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6502348 | 0.82 | EPHX2 (0.36) | EPHX2NR1H4PPARAPPARGITGB1 | |
| SCHEMBL6503712 | 0.82 | PPARA (0.50) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |