Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.44 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210309 | 0.93 | TYR (0.41) | TYRITGB3ITGA2BITGAVPPARA | |
| SCHEMBL6495736 | 0.89 | ITGB3 (0.44) | TYRITGB3ITGA2BITGAVPPARG | |
| SCHEMBL6498071 | 0.88 | ITGB3 (0.44) | TYRITGB3ITGA2BITGAVPPARG | |
| SCHEMBL3052420 | 0.87 | ITGB3 (0.44) | TYRITGB3ITGA2BITGAVPPARG | |
| SCHEMBL6495596 | 0.83 | ITGB3 (0.44) | TYRITGB3ITGA2BITGAVPPARG | |
| SCHEMBL3048114 | 0.83 | ITGB3 (0.44) | TYRITGB3ITGA2BITGAVPPARG | |
| SCHEMBL14431255 | 0.82 | ITGB1 (0.50) | TYRITGB3ITGA2BITGAV | |
| SCHEMBL3048694 | 0.82 | ITGB1 (0.50) | TYRITGB3ITGA2BITGAV | |
| SCHEMBL5205119 | 0.81 | ITGB3 (0.38) | TYRITGB3ITGAVPPARG | |
| SCHEMBL3048231 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849646-B1 | Chromenone and chromanone derivatives as integrin inhibitors | MERCK PATENT GMBH (DE) | 2005-02-01 | — | — | US | disclosed |