Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503652 | 0.83 | CCR8 (0.59) | ALDH1A1SMN1; SMN2PARP10 | |
| SCHEMBL5799166 | 0.82 | NOTUM (0.58) | NOTUM | |
| SCHEMBL6499932 | 0.82 | CYP4F2 (0.61) | NOTUM | |
| SCHEMBL15578214 | 0.82 | HTR1A (0.58) | SCN9ANOTUMALDH1A1SMN1; SMN2FFAR4 | |
| SCHEMBL6506047 | 0.80 | NOTUM (0.57) | SCN9ANOTUMFFAR4PPARA | |
| SCHEMBL18101830 | 0.80 | NOTUM (0.72) | NOTUM | |
| SCHEMBL9161592 | 0.80 | ALOX5 (0.62) | SCN9AALDH1A1LMNAPARP14PARP10 | |
| SCHEMBL5798727 | 0.80 | NOTUM (0.59) | NOTUMSMN1; SMN2FFAR4 | |
| SCHEMBL6498392 | 0.79 | NOTUM (0.85) | NOTUMFFAR4 | |
| SCHEMBL1749207 | 0.79 | NOTUM (0.81) | SCN9ANOTUMALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |