Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489454 | 0.93 | MAOA (0.46) | CYP3A4MAOAMAOBSMN1; SMN2CTNNB1 | |
| SCHEMBL6489521 | 0.93 | SMN1; SMN2 (0.49) | CYP3A4MAOBSMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL6492508 | 0.91 | SMN1; SMN2 (0.52) | CYP3A4SMN1; SMN2CTNNB1TCF7L2L3MBTL1 | |
| SCHEMBL6490637 | 0.90 | CTNNB1 (0.54) | MAOBSMN1; SMN2CTNNB1TCF7L2L3MBTL1 | |
| SCHEMBL6792320 | 0.90 | MAOA (0.50) | CYP3A4MAOAMAOBSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7079728 | 0.90 | SMN1; SMN2 (0.51) | CYP3A4SMN1; SMN2CTNNB1TCF7L2L3MBTL1 | |
| SCHEMBL6499473 | 0.89 | CTNNB1 (0.53) | SMN1; SMN2CTNNB1TCF7L2ALDH1A1NPC1 | |
| SCHEMBL6497909 | 0.87 | SMO (0.52) | SMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL6488828 | 0.86 | CNR1 (0.51) | CYP3A4SMN1; SMN2CTNNB1TCF7L2L3MBTL1 | |
| SCHEMBL6502209 | 0.86 | CTNNB1 (0.50) | CYP3A4MAOBSMN1; SMN2CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | CYP3A4 1368/4885MAOA 258/4885MAOB 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.