Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17854915 | 0.80 | FOXM1 (0.65) | ALDH1A1FDPSMAPTHPGDMEN1 | |
| SCHEMBL3943365 | 0.79 | PPARD (0.58) | ALDH1A1FDPSMAPTHPGDMEN1 | |
| SCHEMBL6504228 | 0.78 | TAAR1 (0.46) | MAPTHPGDMEN1KMT2A | |
| SCHEMBL26936527 | 0.77 | TTR (0.67) | ALDH1A1FDPSMAPTHPGDLMNA | |
| SCHEMBL6503039 | 0.77 | ALDH1A1 (0.51) | ALDH1A1FDPSMAPTHPGDMEN1 | |
| SCHEMBL21331781 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL4769506 | 0.76 | ALDH1A1 (0.53) | ALDH1A1FDPSMAPTHPGDMEN1 | |
| SCHEMBL6504855 | 0.74 | PPARD (0.65) | PPARAPPARGPPARD | |
| SCHEMBL856842 | 0.73 | ALDH1A1 (0.60) | ALDH1A1FDPSMAPTMEN1POLB | |
| SCHEMBL24489133 | 0.73 | ALDH1A1 (0.65) | ALDH1A1FDPSMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |