Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494362 | 0.86 | NPY5R (0.43) | — | |
| SCHEMBL6503221 | 0.83 | MAPT (0.54) | ALDH1A1MAPTTSHRKMT2AL3MBTL1 | |
| SCHEMBL6502018 | 0.81 | PHGDH (0.55) | — | |
| SCHEMBL6505823 | 0.81 | KMT2A (0.41) | KMT2A | |
| SCHEMBL6495617 | 0.78 | MME (0.50) | — | |
| SCHEMBL6505350 | 0.77 | PPARG (0.40) | — | |
| SCHEMBL6497349 | 0.77 | OPRK1 (0.40) | L3MBTL1 | |
| SCHEMBL6496485 | 0.77 | HSD17B10 (0.52) | ALDH1A1MAPTTSHRKMT2AMEN1 | |
| SCHEMBL6503168 | 0.76 | KMT2A (0.39) | KMT2AMEN1 | |
| SCHEMBL6504374 | 0.73 | OPRK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |