Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.35 |
| ▸ | PPARG | P37231 | 8/20 | 0.35 |
| ▸ | PPARD | Q03181 | 5/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497349 | 0.88 | OPRK1 (0.40) | OPRK1RAB9APPARAPPARGPPARD | |
| SCHEMBL6504378 | 0.84 | PPARD (0.40) | PPARAPPARGPPARDSMN1; SMN2LMNA | |
| SCHEMBL6505350 | 0.76 | PPARG (0.40) | OPRK1RAB9APPARAPPARGPPARD | |
| SCHEMBL6496485 | 0.76 | HSD17B10 (0.52) | RAB9ASMN1; SMN2 | |
| SCHEMBL6505823 | 0.75 | KMT2A (0.41) | OPRK1RAB9APPARAPPARGPPARD | |
| SCHEMBL6494362 | 0.73 | NPY5R (0.43) | OPRK1RAB9APPARG | |
| SCHEMBL6503228 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL6497351 | 0.73 | POLB (0.43) | PPARAPPARGPPARDLMNANAMPT | |
| SCHEMBL6502018 | 0.72 | PHGDH (0.55) | — | |
| SCHEMBL6527212 | 0.72 | PPARA (0.45) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |