Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.37 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503228 | 0.86 | ALDH1A1 (0.47) | — | |
| SCHEMBL6494358 | 0.83 | MAPT (0.43) | NPY5R | |
| SCHEMBL6495617 | 0.83 | MME (0.50) | MMEAPLNRRAB9APPARG | |
| SCHEMBL6505350 | 0.81 | PPARG (0.40) | MMECTSAOPRK1RAB9APPARG | |
| SCHEMBL6496485 | 0.80 | HSD17B10 (0.52) | MMERAB9A | |
| SCHEMBL6502018 | 0.78 | PHGDH (0.55) | — | |
| SCHEMBL6505823 | 0.77 | KMT2A (0.41) | OPRK1RAB9APPARG | |
| SCHEMBL6497349 | 0.77 | OPRK1 (0.40) | CTSAOPRK1RAB9APPARG | |
| SCHEMBL6503168 | 0.76 | KMT2A (0.39) | OPRK1RAB9APPARG | |
| SCHEMBL6504374 | 0.73 | OPRK1 (0.36) | OPRK1RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |