Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232906 | 0.87 | PPARA (0.57) | MEN1KMT2APTPN1POLBALDH1A1 | |
| SCHEMBL9831138 | 0.85 | PPARG (0.53) | MEN1KMT2APOLBALDH1A1PPARG | |
| SCHEMBL6231739 | 0.78 | PPARA (0.55) | MEN1KMT2APTPN1ALDH1A1PPARG | |
| SCHEMBL6503416 | 0.77 | POLB (0.46) | MEN1KMT2APTPN1POLBALDH1A1 | |
| SCHEMBL8182679 | 0.77 | PTPN1 (0.79) | MEN1KMT2APTPN1ALDH1A1PPARG | |
| SCHEMBL6495930 | 0.76 | MEN1 (0.46) | MEN1KMT2APTPN1POLBALDH1A1 | |
| SCHEMBL7455356 | 0.75 | PTPN1 (0.63) | PTPN1ALDH1A1PPARGNPSR1MAPT | |
| SCHEMBL8981959 | 0.75 | ALDH1A1 (0.48) | PTPN1ALDH1A1PPARGNPSR1CA2 | |
| SCHEMBL8981944 | 0.75 | ALDH1A1 (0.48) | PTPN1ALDH1A1PPARGNPSR1CA2 | |
| SCHEMBL6231586 | 0.75 | PPARG (0.51) | PTPN1PPARGMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213287-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | disclosed |
| EP-1213287-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |