Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499575 | 0.91 | ALDH1A1 (0.43) | HDAC2HDAC1FAAH | |
| SCHEMBL8499772 | 0.91 | ALDH1A1 (0.43) | HDAC2HDAC1FAAH | |
| SCHEMBL8496246 | 0.91 | ALDH1A1 (0.43) | HDAC2HDAC1FAAH | |
| SCHEMBL5399646 | 0.91 | MMP12 (0.44) | HDAC2HDAC1MMP12MCHR1HRH3 | |
| SCHEMBL6508362 | 0.89 | RARB (0.48) | FAAH | |
| SCHEMBL6502423 | 0.89 | RARB (0.45) | FAAH | |
| SCHEMBL8499606 | 0.86 | POLB (0.42) | FAAH | |
| SCHEMBL8498944 | 0.85 | TNNC1 (0.45) | SLC6A2FAAH | |
| SCHEMBL8499405 | 0.85 | TNNC1 (0.42) | FAAH | |
| SCHEMBL8499864 | 0.85 | TNNC1 (0.45) | SLC6A2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |