Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743063 | 0.81 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL1544471 | 0.77 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL6504213 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL2801067 | 0.77 | FDPS (0.57) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL13701663 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL10339477 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL13702388 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL364320 | 0.74 | SMARCA2 (0.49) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL29640105 | 0.74 | SMARCA2 (0.49) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL24568629 | 0.74 | PREP (0.50) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |