Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944485 | 0.84 | PI4KB (0.51) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12742401 | 0.84 | PTPRB (0.49) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28584083 | 0.84 | SIRT1 (0.46) | PI4KBSIRT1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6495932 | 0.83 | AOC3 (0.54) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2668827 | 0.83 | SIRT1 (0.48) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL299175 | 0.82 | SMN1; SMN2 (0.51) | PI4KBSIRT1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24434982 | 0.81 | AOC3 (0.53) | SIRT1SMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL1030124 | 0.81 | PI4KB (0.50) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2175797 | 0.81 | SMN1; SMN2 (0.50) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6679893 | 0.80 | SIRT1 (0.49) | PI4KBSIRT1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | PI4KB 1625/4885SIRT1 804/4885ALDH1A1 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.