Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079979 | 0.86 | L3MBTL1 (0.56) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL15079417 | 0.84 | MAPT (0.61) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL9854725 | 0.82 | TAAR1 (0.56) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL6504762 | 0.78 | ALDH1A1 (0.48) | MAPTHPGDMEN1KMT2A | |
| SCHEMBL3903691 | 0.77 | TAAR1 (0.50) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL6721565 | 0.73 | TAAR1 (0.46) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL24041823 | 0.73 | BCHE (0.46) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL11347476 | 0.73 | L3MBTL1 (0.46) | TAAR1MAPTHPGDATML3MBTL1 | |
| SCHEMBL15080025 | 0.73 | L3MBTL1 (0.67) | TAAR1MAPTL3MBTL1KCNH2MEN1 | |
| SCHEMBL12409059 | 0.72 | NOS1 (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |