Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505239 | 0.84 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL6508806 | 0.82 | DRD2 (0.45) | — | |
| SCHEMBL13528608 | 0.80 | CA2 (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL9847625 | 0.77 | ALDH1A1 (0.43) | POLB | |
| SCHEMBL13766521 | 0.75 | DRD2 (0.48) | CYP4F2CYP4A11ESR1ESR2CHRM1 | |
| SCHEMBL27687698 | 0.75 | DRD2 (0.48) | CYP4F2CYP4A11ESR1ESR2CHRM1 | |
| SCHEMBL12660944 | 0.74 | CYP4F2 (0.64) | CYP4F2CYP4A11POLB | |
| SCHEMBL10262750 | 0.74 | CREBBP (0.41) | ESR1ESR2 | |
| SCHEMBL6498134 | 0.72 | ESR2 (0.45) | ESR1ESR2 | |
| SCHEMBL10506130 | 0.72 | DRD2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841183-B2 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20020127320-A1 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1227104-A1 | PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATES | Ajinomoto Co., Inc. (JP) | 2002-07-31 | — | — | EP | disclosed |