Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471402 | 0.98 | LNPEP (0.43) | LNPEPTDP1L3MBTL1KDM4EKAT8 | |
| SCHEMBL6507963 | 0.95 | LNPEP (0.39) | LNPEPTDP1L3MBTL1KDM4ECYP3A4 | |
| SCHEMBL6510156 | 0.88 | NOS2 (0.36) | LNPEPL3MBTL1KDM4ECYP3A4LMNA | |
| SCHEMBL5509083 | 0.83 | HSD17B10 (0.45) | LNPEPTDP1L3MBTL1KDM4ELPL | |
| SCHEMBL7467453 | 0.82 | CA2 (0.38) | LNPEPKDM4E | |
| SCHEMBL10992432 | 0.82 | HSD17B10 (0.47) | TDP1L3MBTL1KDM4ELPLLIPG | |
| SCHEMBL7694745 | 0.82 | HSD17B10 (0.47) | TDP1L3MBTL1KDM4ELPLLIPG | |
| SCHEMBL9440126 | 0.82 | HSD17B10 (0.47) | TDP1L3MBTL1KDM4ELPLLIPG | |
| SCHEMBL7472832 | 0.81 | CA2 (0.35) | LNPEPPPARA | |
| SCHEMBL6509903 | 0.80 | NOS3 (0.52) | L3MBTL1KDM4ELMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |