Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156696 | 0.85 | EPHX2 (0.64) | EPHX2KMT2AGAAL3MBTL1POLB | |
| SCHEMBL2403269 | 0.85 | KMT2A (0.71) | EPHX2KMT2AGAAL3MBTL1POLB | |
| SCHEMBL198282 | 0.84 | ALDH1A1 (0.62) | EPHX2KMT2AGAAPOLBKDM4E | |
| SCHEMBL29626821 | 0.84 | ALDH1A1 (0.62) | EPHX2KMT2AGAAPOLBKDM4E | |
| SCHEMBL602779 | 0.83 | EPHX2 (0.62) | EPHX2KMT2AGAAL3MBTL1POLB | |
| SCHEMBL8259636 | 0.81 | KMT2A (0.62) | EPHX2KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11187045 | 0.80 | LMNA (0.63) | EPHX2KMT2AGAAPOLBKDM4E | |
| SCHEMBL30859524 | 0.80 | LMNA (0.63) | EPHX2KMT2AGAAPOLBKDM4E | |
| SCHEMBL2406403 | 0.80 | SIGMAR1 (0.70) | EPHX2KMT2AGAAL3MBTL1POLB | |
| SCHEMBL17993526 | 0.80 | KMT2A (0.64) | EPHX2KMT2AGAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |