Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528645 | 0.75 | TSHR (0.55) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL592296 | 0.72 | ALDH1A1 (0.63) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL10305252 | 0.71 | ROCK2 (0.67) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6512420 | 0.70 | MGLL (0.43) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6512417 | 0.70 | MGLL (0.43) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL589813 | 0.70 | NPC1 (0.85) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6529831 | 0.70 | NPC1 (0.48) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6509761 | 0.70 | MGLL (0.43) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6509758 | 0.70 | MGLL (0.43) | ALDH1A1NPC1TP53MAPTTSHR | |
| SCHEMBL6532124 | 0.69 | NPC1 (0.60) | ALDH1A1NPC1TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |