Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 3/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | HEXD | Q8WVB3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496051 | 0.92 | PPARG (0.41) | SHMT1SHMT2PPARAPPARGPPARD | |
| SCHEMBL6496502 | 0.92 | PPARA (0.39) | PPARAPPARGPPARDWDR5MAPT | |
| SCHEMBL6496225 | 0.89 | WDR5 (0.36) | SHMT1SHMT2PPARAPPARGPPARD | |
| SCHEMBL6504835 | 0.86 | PPARG (0.43) | PPARAPPARGPPARD | |
| SCHEMBL7676301 | 0.86 | PPARG (0.43) | PPARAPPARGPPARDWDR5 | |
| SCHEMBL6505578 | 0.84 | PPARG (0.41) | PPARAPPARGPPARD | |
| SCHEMBL6495540 | 0.83 | THRB (0.43) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6502884 | 0.83 | PPARG (0.43) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL6503008 | 0.83 | PPARG (0.48) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.82 | SHMT1 (0.44) | SHMT1SHMT2PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |