Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344793 | 1.00 | TSHR (0.42) | TSHRKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL6503292 | 0.90 | ALDH1A1 (0.35) | TSHRPOLBALDH1A1NPSR1EPHX2 | |
| SCHEMBL6427696 | 0.85 | DPP8 (0.34) | TSHRALDH1A1EPHX2KDM4ETDP1 | |
| SCHEMBL6427367 | 0.84 | MAPT (0.37) | TSHRALDH1A1EPHX2KDM4ETDP1 | |
| SCHEMBL6427323 | 0.83 | DPP4 (0.40) | KMT2AALDH1A1MEN1NPSR1KDM4E | |
| SCHEMBL6427655 | 0.82 | LMNA (0.36) | — | |
| SCHEMBL6426304 | 0.81 | EPHX2 (0.34) | TSHRKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL6507788 | 0.80 | ALDH1A1 (0.39) | TSHRKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL6426277 | 0.80 | ALDH1A1 (0.43) | TSHRKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL6426662 | 0.80 | EPHX2 (0.36) | KMT2APOLBALDH1A1MEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | TSHR 2078/4885KMT2A 3213/4885POLB 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.