Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505000 | 0.83 | KDM4E (0.41) | L3MBTL1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL6427866 | 0.78 | KDM4E (0.57) | L3MBTL1NPC1RAB9AKDM4EGFER | |
| SCHEMBL6602729 | 0.76 | L3MBTL1 (0.74) | L3MBTL1KDM4EALDH1A1PTGDR2POLB | |
| SCHEMBL3436188 | 0.75 | KDM4E (0.63) | TDP1NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL6431720 | 0.75 | L3MBTL1 (0.56) | L3MBTL1NPC1RAB9AKDM4EGFER | |
| SCHEMBL3436687 | 0.73 | METAP2 (0.39) | KDM4EGFERKMT2AMAPTALDH1A1 | |
| SCHEMBL6502484 | 0.73 | L3MBTL1 (0.58) | L3MBTL1NPC1RAB9AKDM4EGFER | |
| SCHEMBL5238288 | 0.73 | L3MBTL1 (0.58) | L3MBTL1KDM4EALDH1A1PTGDR2 | |
| SCHEMBL13453775 | 0.72 | HDAC3 (0.58) | L3MBTL1 | |
| SCHEMBL19207072 | 0.72 | NTRK1 (0.41) | L3MBTL1TDP1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |