Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504157 | 0.89 | CCR8 (0.66) | CCR8KDM4EALDH1A1SIGMAR1MEN1 | |
| SCHEMBL6498562 | 0.82 | CCR8 (0.60) | CCR8KDM4EALDH1A1SIGMAR1MEN1 | |
| SCHEMBL6496921 | 0.82 | CCR8 (0.60) | CCR8KDM4EALDH1A1SIGMAR1MEN1 | |
| SCHEMBL6943757 | 0.82 | SIGMAR1 (0.68) | KDM4EALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL6501369 | 0.81 | CCR8 (0.86) | CCR8SIGMAR1KCNH2TSHR | |
| Hydrochloric Acid SCHEMBL11535920 | 0.81 | SIGMAR1 (0.67) | KDM4EALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL6501384 | 0.78 | ALDH1A1 (0.66) | CCR8KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL8352314 | 0.78 | SIGMAR1 (0.59) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL6943838 | 0.78 | BACE1 (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6506424 | 0.77 | CCR8 (0.63) | CCR8SIGMAR1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | CCR8 1/4885KDM4E 4617/4885ALDH1A1 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.