Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508806 | 0.85 | DRD2 (0.45) | CA2CA5ADRD2DRD3FFAR1 | |
| SCHEMBL9847659 | 0.83 | ALDH1A1 (0.46) | DRD2DRD3 | |
| SCHEMBL6495993 | 0.81 | CA2 (0.48) | CA2CA5ADRD2DRD3FFAR1 | |
| SCHEMBL6495855 | 0.81 | ESR1 (0.56) | — | |
| SCHEMBL27610321 | 0.81 | ESR1 (0.36) | DRD2DRD3 | |
| SCHEMBL6497031 | 0.80 | HTR6 (0.56) | CA2CA5A | |
| SCHEMBL7321911 | 0.78 | FFAR1 (0.52) | CA2CA5ADRD2DRD3FFAR1 | |
| SCHEMBL7316922 | 0.78 | FFAR1 (0.52) | CA2CA5ADRD2DRD3FFAR1 | |
| SCHEMBL27610322 | 0.78 | ESR1 (0.34) | — | |
| SCHEMBL14857588 | 0.78 | FFAR1 (0.45) | CA2CA5AFFAR1CYP19A1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841183-B2 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20020127320-A1 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1227104-A1 | PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATES | Ajinomoto Co., Inc. (JP) | 2002-07-31 | — | — | EP | disclosed |