Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433103 | 0.92 | SMN1; SMN2 (0.58) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10979533 | 0.86 | L3MBTL1 (0.54) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10983103 | 0.84 | SMN1; SMN2 (0.58) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL9399929 | 0.83 | THRA (0.53) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL9398890 | 0.83 | THRA (0.53) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10974737 | 0.83 | SMN1; SMN2 (0.61) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10980032 | 0.83 | SMN1; SMN2 (0.61) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL9399173 | 0.82 | SMN1; SMN2 (0.59) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10980962 | 0.82 | SMN1; SMN2 (0.59) | GLASMN1; SMN2S1PR1BACE1ATM | |
| SCHEMBL10979485 | 0.81 | MAPT (0.52) | GLASMN1; SMN2S1PR1BACE1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014534-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |